Term Name: myriocin
Synonyms: (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid, (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid, (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid, antibiotic ISP-1, antibiotic ISP-I, ISP-1, ISP-I, thermozymocidin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Ontology: ChEBI [CHEBI:582124]  ( EBI )

Relationships
is a type of: alpha-amino fatty acid hydroxy monocarboxylic acid non-proteinogenic alpha-amino acid sphingoid
has_role: antifungal agent antimicrobial agent antineoplastic agent apoptosis inducer EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor fungal metabolite immunosuppressive agent