Term Name: | encainide |
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Synonyms: | (+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide, (+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide, 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide, 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide, 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide, encainida, encainide, encainidum |
Definition: | 4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. |
Ontology: | ChEBI [CHEBI:4788] ( EBI ) |