Term Name: | edrophonium chloride |
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Synonyms: | (3-hydroxyphenyl)dimethylethylammonium chloride, 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride, chlorure d'edrophonium, cloruro de edrofonio, edrophonii chloridum, edrophonium chloride, ethyl(m-hydroxyphenyl)dimethylammonium chloride, N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride, N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride |
Definition: | The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals. |
Ontology: | ChEBI [CHEBI:4759] ( EBI ) |