Term Name: | diazoxide |
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Synonyms: | 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Diazossido, diazoxide, diazoxido, diazoxidum, Eudemine |
Definition: | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. |
Ontology: | ChEBI [CHEBI:4495] ( EBI ) |