Term Name:	EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Synonyms:	HMG-CoA reductase inhibitor, HMG-CoA reductase inhibitors, hydroxymethylglutaryl-CoA reductase inhibitor, hydroxymethylglutaryl-CoA reductase inhibitors
Definition:	Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
Ontology:	ChEBI [CHEBI:35664]  ( EBI )