Term Name: | dizocilpine |
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Synonyms: | (+)-dizocilpine, (+)-MK-801, (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, dizocilpina, dizocilpine, dizocilpinum, MK 801, MK-801, MK801 |
Definition: | An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. |
Ontology: | ChEBI [CHEBI:34725] ( EBI ) |