Term Name: tolvaptan
Synonyms: (+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide, (+-)-tolvaptan, (RS)-tolvaptan, Jinarc, Jynarque, N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide, OPC 41061, OPC-41061, rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide, RS-tolvaptan, Samsca, tolvaptan, tolvaptanum
Definition: A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency.
Ontology: ChEBI [CHEBI:32246]  ( EBI )

Relationships
is a type of: racemate
has_part: (R)-tolvaptan (S)-tolvaptan
has_role: aquaretic vasopressin receptor antagonist
inverse has_functional_parent: DM-4103 DM-4107