Term Name: calciol
Synonyms: (+)-vitamin D3, (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol, activated 7-dehydrocholesterol, calciol, CC, Cholecalciferol, colecalciferol, Delta-D, oleovitamin D3, vitamin D3
Definition: A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.
Ontology: ChEBI [CHEBI:28940]  ( EBI )

Relationships
is a type of: D3 vitamins hydroxy seco-steroid seco-cholestane secondary alcohol steroid hormone
has_role: geroprotector human metabolite
inverse has_functional_parent: (24R)-1alpha,24-dihydroxy-22-oxavitamin D3 1alpha,2beta,25-trihydroxy vitamin D3 1alpha,23(S),25-trihydroxyvitamin D3 5,6-trans-vitamin D3 alfacalcidol hydroxycalciol oxocalciol tacalcitol