Term Name: | acadesine |
---|---|
Synonyms: | 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide, 5-amino-1-beta-D-ribofuranosyl-4-imidazolecarboxamide, 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide, 5-amino-1-beta-ribofuranosyl-imidazole-4-carboxamide, 5-amino-1-ribofuranosylimidazole-4-carboxamide, 5-amino-1beta-D-ribofuranosylimidazole-4-carboxyamide, 5-amino-4-imidazolecarboxamide ribofuranoside, 5-aminoimidazole-4-carboxamide ribonucleoside, acadesina, acadesine, acadesinum, AIC-Riboside, AICA-riboside, AICAr, EC Number 220-097-5, GP 1-110, GP-1-110, N(1)-(beta-D-ribofuranosyl)-5-aminoimidazole-4-carboxamide |
Definition: | A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. |
Ontology: | ChEBI [CHEBI:28498] ( EBI ) |