Term Name:	mutagen
Synonyms:	mutagene, mutagenes, mutagenic agent, mutageno, mutagenos, mutagens
Definition:	An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
Ontology:	ChEBI [CHEBI:25435] ( EBI )

Relationships

is a type of:	genotoxin
has subtype:	alkylating agent intercalator
inverse has_role:	(2E)-dec-2-enal (E)-4-nitrostilbene (S)-colchicine 1,1-dichloroethene 1,2-dibromoethane 1,2-dichloroethane 1,2:7,8-diepoxyoctane 1-bromo-2-chloroethane 1-methoxy-N-nitrosodiethylamine 1-methylphenanthrene 1H-imidazo[2,1-i]purine 2,5-bis(aziridin-1-yl)-1,4-benzoquinone 2,6-diaminotoluene 2-acetamidofluorene 2-amino-6-hydroxyaminopurine 2-nitrofluorene 3,4-epoxy-1-cyclohexene 3,N(4)-ethenocytosine 3-acetyl-2,5-dimethylfuran 4-amino-3-hydroxynaphthalene-1-sulfonic acid 4-aminofolic acid 4-methylquinoline 4-nitroanthranilic acid 4-nitrophenylhydrazine 5-bromouracil 5-bromouridine 5-fluorouridine 5-formyluracil 6,12-dimethyldibenzo[d,d']benzo[1,2-b:4,5-b']bisthiophene 6-O-methylguanine 7-bromomethyl-12-methyltetraphene 8-oxo-dGTP 9-aminoacridine 9-aminoacridine hydrochloride 11,12-epoxy-3-methylcholanthrene acetaldehyde acridine half-mustard acridine half-mustard dihydrochloride acrylamide acrylonitrile actinomycin D aristolochic acid A aristolochic acid B aristolochic acid C Bandrowski's base bellidin benz[a]anthracene 5,6-oxide benzo[b]fluoranthene benzo[e]pyrene buta-1,3-diene caffeine carboplatin chloromethane cisplatin dibenz[a,h]anthracene dibenzo[a,l]pyrene diepoxybutane diethyl sulfate dimethylmyleran epibromohydrin ethyl methanesulfonate fagaronine hesperidin hexamethylphosphoric triamide hycanthone hycanthone mesylate ICR 340 iron(III) nitrilotriacetate lucanthone MeIQx methoxyacetic acid methyl methanesulfonate Methyl violet 2B myosmine N(6)-hydroxyadenine N-[2-chloro-2-(naphthalen-2-yl)ethyl]propan-2-amine hydrochloride N-acetoxy-2-acetamidofluorene N-ethyl-N-nitrosourea N-hydroxy-MeIQx N-hydroxy-PhIP N-methyl-N-nitrosourea N-nitrosodiethylamine N-nitrosodimethylamine N-nitrosomorpholine N-nitrosopiperidine nitrosocarbaryl oxaliplatin oxirane ozone p-N,N-bis(2-chloroethyl)amino-D-phenylalanine p-N,N-bis(2-chloroethyl)amino-L-phenylalanine p-N,N-bis(2-chloroethyl)aminophenylvaleric acid p-nitrobenzyl chloride p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine patulin phenanthridone PhIP phleomycin riddelliine riddelliine N-oxide S-2-chloroethylcysteine sodium azide sodium fluoride sodium hydrogensulfite sodium methoxyacetate Solvent yellow 56 spiroiminodihydantoin styrene urethane