Term Name:	edrophonium
Synonyms:	(3-hydroxyphenyl)dimethylethylammonium, 3-hydroxy-N,N-dimethyl-N-ethylanilinium, edrophonium, EDROPHONIUM ION, Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium, N-ethyl-3-hydroxy-N,N-dimethylanilinium, N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium
Definition:	A quaternary ammonium ion that is N-ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Ontology:	ChEBI [CHEBI:251408]  ( EBI )