Term Name: | adefovir |
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Synonyms: | 9-(2-(Phosphonomethoxy)ethyl)adenine, 9-(2-Phosphonylmethoxyethyl)adenine, Adefovir, DRG-0156, GS 0393, GS 393, GS-0393, HSDB 8079, N-(2-Phosphonylmethoxyethyl)adenine, PMEA, {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid |
Definition: | A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection. |
Ontology: | ChEBI [CHEBI:2469] ( EBI ) |