Term Name: | tasisulam |
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Synonyms: | LY 573636, LY-573636, LY573636, N-(2,4-dichlorobenzoyl)-5-bromothiophene-2-sulfonamide, N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide, N-[(5-bromothiophen-2-yl)sulfonyl]-2,4-dichlorobenzamide, tasisulam, tasisulamum |
Definition: | A thiophene substituted by a 2,4-dichlorobenzamide-N-sulfonyl and bromo groups at positions 2 and 4, respectively. It induces tumour cell apoptosis via ROS induction and mitochondrial membrane potential loss and currently in clinical development for the treatment of cancer. |
Ontology: | ChEBI [CHEBI:231621] ( EBI ) |