Term Name: sulfopin
Synonyms: 2-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-neopentylacetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda(6)-thiolan-3-yl)acetamide, PIN1-3
Definition: A sulfone that is thiolane substituted by two oxo groups at position 1 and by a (chloroacetyl)(2,2-dimethylpropyl)amino group at position 3. It is a covalent inhibitor of Pin1 (Ki = 17 nM) that inhibits Myc-driven tumors in vivo.
Ontology: ChEBI [CHEBI:231413]  ( EBI )

Relationships
is a type of: organochlorine compound sulfone tertiary carboxamide tetrahydrothiophenes
has_role: antineoplastic agent EC 5.2.* (cis-trans-isomerase) inhibitor