Term Name: | orteronel |
---|---|
Synonyms: | (+)-orteronel, (S)-orteronel, 6-[(7S)-7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide, orteronel, orteronelum, TAK 700, TAK-700, TAK700 |
Definition: | A member of the class of pyrroloimidazoles that is 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole substituted by hydroxy and 6-(methylcarbamoyl)naphthalen-2-yl groups at position 7 (the 7S-stereoisomer). It is a non-steroidal 17,20-lyase inhibitor that suppresses androgen synthesis. It was previously in clinical development for the treatment of castration-resistant prostate cancer -- trial now discontinued. |
Ontology: | ChEBI [CHEBI:231353] ( EBI ) |