Term Name: | iptacopan |
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Synonyms: | 4-{(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl}benzoic acid, iptacopan, iptacopanum, LNP 023, LNP-023, LNP023, NVP-LNP023 |
Definition: | A member of the class of indoles that is 1H-indole substituted by [(2S,4S)-2-(4-carboxyphenyl)-4-ethoxypiperidin-1-yl]methyl, methoxy, and methyl groups at positions 4, 5, and 6, respectively. It is a potent inhibitor of complement factor B (IC50 = 10nM) with potential immunomodulatory activity. |
Ontology: | ChEBI [CHEBI:229652] ( EBI ) |