Term Name: | TA-1887 |
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Synonyms: | (2R,3R,4S,5S,6R)-2-[3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol, 3-(4-cyclopropylbenzyl)-4-fluoro-1-beta-D-glucopyranosyl-1H-indole, 3-(4-cyclopropylbenzyl)-4-fluoroindole-N-glucoside, 3-[(4-cyclopropylphenyl)methyl]-4-fluoro-1-beta-D-glucopyranosyl-1H-indole, JNJ 39933673, JNJ-39933673, JNJ39933673, TA 1887, TA1887 |
Definition: | A fluoroindole that is 1H-indole substituted by a beta-D-glucopyranosyl, 4-cyclopropylbenzyl, and fluoro groups at positions 1, 3 and 4, respectively. It is a highly potent and selective SGLT2 inhibitor, with antihyperglycemic effects in high-fat diet-fed KK mice. |
Ontology: | ChEBI [CHEBI:229237] ( EBI ) |