Term Name: | repotrectinib |
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Synonyms: | (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one, Augtyro, repotrectinib, repotrectinibum, TPX 0005, TPX-0005, TPX0005 |
Definition: | An azamacrocycle with formula C18H18FN5O2. It is a tyrosine kinase inhibitor (highly potent against ROS1, TRKA-C, and ALK) used for the treatment of locally advanced or metastatic ROS1-positive non-small cell lung cancer. |
Ontology: | ChEBI [CHEBI:229220] ( EBI ) |