Term Name: mocetinostat
Synonyms: MG 0103, MGCD 0103, MGCD-0103, MGCD0103, mocetinostat, mocetinostatum, N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide
Definition: A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).
Ontology: ChEBI [CHEBI:197437]  ( EBI )

Relationships
is a type of: aminopyrimidine benzamides pyridines secondary amino compound secondary carboxamide substituted aniline
has_role: antineoplastic agent apoptosis inducer autophagy inducer cardioprotective agent EC 3.5.1.98 (histone deacetylase) inhibitor hepatotoxic agent