Term Name: | lobaplatin |
---|---|
Synonyms: | 1,2-diamino-methylcyclobutane platinum(II) lactate, 1,2-diamino-methylcyclobutane-platinum(II) lactate, [2-hydroxypropanoato(2-)-O1,O2][1,2-cyclobutanedimethanamine-N,N']platinum(II), D 19466, D-19466, D19466, lobaplatin, lobaplatine, lobaplatino, lobaplatinum |
Definition: | A 1:1 diastereomeric mixture comprising of R,R,S and S,S,S configuration of platinum(II) complexes with 1,2-bis(aminomethyl)cyclobutane as the carrier ligand and lactate as the leaving group. It is a third-generation platinum anticancer drug approved in China for the treatment of chronic myelogenous leukaemia, inoperable metastatic breast cancer and small cell lung cancer. |
Ontology: | ChEBI [CHEBI:192744] ( EBI ) |