Term Name:	RepSox
Synonyms:	2-(3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, 2-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine, ALK5 Inhibitor II, E 616452, E-616452, E616452, SJN 2511, SJN-2511, SJN2511, TGF-beta RI Kinase Inhibitor II
Definition:	A member of the class of pyrazoles that is 1H-pyrazole substituted by 6-methylpyridin-2-yl and 1,5-naphthyridin-2-yl groups at positions 3 and 4, respectively. It is a potent and selective inhibitor of TGF-beta R1 kinase (IC50 = 4 nM) and ALK5 autophosphorylation and binding (IC50 = 23 nM).
Ontology:	ChEBI [CHEBI:190969]  ( EBI )