Term Name: calcitriol
Synonyms: (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, 1,25-DHCC, 1-alpha-25-Dihydroxyvitamin D3, 1alpha,25(OH)2D3, 1alpha,25-dihydroxycholecalciferol, 1alpha,25-dihydroxyvitamin D3, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Calcijex, Calcitriol, calcitriolum, Decostriol, Rocaltrol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Ontology: ChEBI [CHEBI:17823]  ( EBI )

Relationships
is a type of: D3 vitamins hydroxycalciol triol
has_role: antineoplastic agent antipsoriatic bone density conservation agent calcium channel agonist calcium channel modulator hormone human metabolite immunomodulator metabolite mouse metabolite nutraceutical
inverse has_functional_parent: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 1alpha,25-dihydroxy-2beta-(4-hydroxybutoxy)vitamin D3 18-acetoxy-1alpha,25-dihydroxyvitamin D3 AMCR277A AMCR277B calcitriol 25-O-(beta-D-glucuronate) calcitriol 25-O-(beta-D-glucuronide) calcitriol 26,23-lactone