Term Name: | 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide |
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Synonyms: | (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]-2H-indazole-7-carboxamide, 2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide, 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, ent-niraparib, MK-4827 (R-enantiomer), niraparib (R-enantiomer) |
Definition: | A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. |
Ontology: | ChEBI [CHEBI:177299] ( EBI ) |