Term Name: cortisol
Synonyms: (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, 17-hydroxycorticosterone, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, cortisol, hidrocortisona, Hydrocortisone, hydrocortisonum, Kendall's compound F, Reichstein's substance M
Definition: A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.
Ontology: ChEBI [CHEBI:17650]  ( EBI )

Relationships
is a type of: 3-oxo-Delta(4) steroid 11beta-hydroxy steroid 17alpha-hydroxy-C21-steroid 20-oxo steroid 21-hydroxy steroid glucocorticoid primary alpha-hydroxy ketone tertiary alpha-hydroxy ketone
has_parent_hydride: pregnane
has_role: anti-allergic agent anti-asthmatic drug anti-inflammatory drug drug allergen human metabolite mouse metabolite
inverse has_functional_parent: 6beta-hydroxycortisol 18-hydroxycortisol 18-oxocortisol 20beta-dihydrocortisol cortisol ester deoxycortisol hydrocortisone caproate hydrocortisone succinate