Term Name: | ML162 |
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Synonyms: | 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-{2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}acetamide, DPI7, ML 162, ML-162, Molecular Libraries 162 |
Definition: | A monochlorobenzene that is benzene substituted by (chloroacetyl){2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}amino, chloro and methoxy groups at positions 1, 3 and 4, respectively. It is a covalent inhibitor of glutathione peroxidase 4 (GPX4) that induces ferroptosis in cells. |
Ontology: | ChEBI [CHEBI:176499] ( EBI ) |