Term Name: | 5-aminolevulinic acid |
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Synonyms: | 5-ALA, 5-Amino-4-oxopentanoate, 5-amino-4-oxopentanoic acid, 5-Amino-4-oxovaleric acid, 5-Aminolevulinate, aminolevulinic acid, dALA, delta-ALA, delta-aminolevulinic acid |
Definition: | The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. |
Ontology: | ChEBI [CHEBI:17549] ( EBI ) |