Term Name: AZD3463
Synonyms: AZD 3463, AZD-3463, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)-2-pyrimidinamine, N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
Definition: A member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK.
Ontology: ChEBI [CHEBI:167653]  ( EBI )

Relationships
is a type of: aminopiperidine aminopyrimidine indoles monomethoxybenzene organochlorine compound secondary amino compound tertiary amino compound
has_role: antineoplastic agent apoptosis inducer autophagy inducer EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor