Term Name: | monomethyl fumarate |
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Synonyms: | (2E)-4-methoxy-4-oxobut-2-enoic acid, (E)-4-methoxy-4-oxobut-2-enoic acid, Bafiertam, fumarate de monomethyle, fumarato de monometilo, fumaric acid monomethyl ester, methyl hydrogen fumarate, mono-methyl fumarate, monomethyl fumarate, monomethylfumarate, monomethylis fumaras |
Definition: | A dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1. |
Ontology: | ChEBI [CHEBI:167450] ( EBI ) |