Term Name: | phevalin |
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Synonyms: | 3-(1-methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone, 6-benzyl-3-(propan-2-yl)-1,2-dihydropyrazin-2-one, 6-benzyl-3-(propan-2-yl)pyrazin-2(1H)-one, 6-benzyl-3-isopropyl-1H-pyrazin-2-one, 6-benzyl-3-propan-2-yl-1H-pyrazin-2-one, aureusimine B |
Definition: | A member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 muM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression. |
Ontology: | ChEBI [CHEBI:167320] ( EBI ) |