Term Name: dextromethadone
Synonyms: (+)-(S)-6-(dimethylamino)-4,4-diphenyl-3-heptanone, (+)-methadone, (6S)-6-(dimethylamino)-4,4-diphenylheptan-3-one, (6S)-methadone, (S)-(+)-methadone, (S)-6-(dimethylamino)-4,4-diphenyl-3-heptanone, (S)-methadone, d-6-(dimethylamino)-4,4-diphenyl-3-heptanone, d-methadone, REL-1017, S-(+)-methadone, S-methadone
Definition: A 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder.
Ontology: ChEBI [CHEBI:167308]  ( EBI )

Relationships
is a type of: 6-(dimethylamino)-4,4-diphenylheptan-3-one
has_role: NMDA receptor antagonist opioid analgesic
inverse has_part: methadone
inverse is_enantiomer_of: levomethadone
is_enantiomer_of: levomethadone