Term Name: | Glu-Gly-Arg-chloromethylketone |
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Synonyms: | chloromethylketone-EGR, EGR-chloromethylketone, EGR-CMK, EGRCK, Glu-Gly-Arg-chloromethylketone, glutamyl-glycyl-arginine chloromethyl ketone, H-Glu-Gly-Arg-CH2Cl, H-Glu-Gly-Arg-chloromethylketone, L-alpha-glutamyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]glycinamide, L-Glu-Gly-L-Arg-chloromethylketone |
Definition: | A tripeptide composed of L-glutamic acid, glycine and L-arginine joined in sequence by peptide linkages and in which the carboxy terminus is substituted by a chloroacetyl group. It is a potent and irreversible inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa. |
Ontology: | ChEBI [CHEBI:157651] ( EBI ) |