Term Name: | 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil |
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Synonyms: | 4'-OH-butyl-5-OP-U, 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione, 6-[(4-hydroxybutyl)amino]-5-[[(1E)-2-oxopropylidene]amino]-2,4(1H,3H)-pyrimidinedione |
Definition: | A nucleobase analogue that is uracil substituted with a (4-hydroxybutyl)amino group at position 6 and an (E)-(2-oxopropylidene)amino group at position 5; one of 20 modifications to the potent microbial riboflavin-based metabolite antigen 5-(2-oxopropylideneamino)-6-D-ribityl aminouracil (5-OP-RU), an activator of mucosal-associated invariant T (MAIT) cells when presented by the MR1 protein (reported in MED:32123373). |
Ontology: | ChEBI [CHEBI:149748] ( EBI ) |