Term Name: | 6-methyl-5-[(1E)-3-oxobut-1-en-1-yl]uracil |
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Synonyms: | 6-methyl-5-[(1E)-3-oxo-1-buten1-yl]-2,4(1H,3H)-pyrimidinedione, 6-methyl-5-[(1E)-3-oxobut-1-en-1-yl]pyrimidine-2,4(1H,3H)-dione |
Definition: | A nucleobase analogue that is uracil substituted with a methyl group at position 6 and a (1E)-3-oxobut-1-en-1-yl group at position 5; one of 20 modifications to the potent microbial riboflavin-based metabolite antigen 5-(2-oxopropylideneamino)-6-D-ribityl aminouracil (5-OP-RU), an activator of mucosal-associated invariant T (MAIT) cells when presented by the MR1 protein (reported in MED:32123373). |
Ontology: | ChEBI [CHEBI:149702] ( EBI ) |