Term Name: | 6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir |
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Synonyms: | (1S,4R)-4-[2-amino-6-[[(1S)-1-methylpropyl]amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol, 6-de(cyclopropylamino)-6-(S-sec-butylamino)abacavir, [(1S,4R)-4-{2-amino-6-[(2S)-butan-2-ylamino]-9H-purin-9-yl}cyclopent-2-en-1-yl]methanol |
Definition: | A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by an (S)-sec-butylamino group. One of a series of synthesised abacavir analogues with antiviral activity found to stimulate IFN-gamma secretion in abacavir-responsive clones. |
Ontology: | ChEBI [CHEBI:149438] ( EBI ) |