Term Name: | VPC 23019 |
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Synonyms: | (2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate, (2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide, (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester, N-(3-octylphenyl)-O-phosphono-D-serinamide, VPC-23019, VPC23019 |
Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. |
Ontology: | ChEBI [CHEBI:144948] ( EBI ) |