Term Name: (R)-homocamptothecin
Synonyms: (5R)-5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione, HCPT, homocamptothecin
Definition: An organic heteropentacyclic compound that is (5R)-5-ethyl-5-hydroxy-8-(quinolin-3-ylmethyl)-1,4,5,8-tetrahydrooxepino[3,4-c]pyridine-3,9-dione in which position 7 of the oxepinopyridine group has been joined to position 2 of the quinoline ring by a single bond. A semisynthetic analogue of camptothecin, it is an inhibitor of topoisomerase I.
Ontology: ChEBI [CHEBI:144047]  ( EBI )

Relationships
is a type of: epsilon-lactone organic heteropentacyclic compound organonitrogen heterocyclic compound tertiary alcohol
has_role: antineoplastic agent EC 5.99.1.2 (DNA topoisomerase) inhibitor
inverse has_functional_parent: diflomotecan