Term Name: andrastin A
Synonyms: methyl (3beta,5beta,8alpha,9beta,10alpha,13alpha)-3-acetoxy-15-hydroxy-4,4,8,12,16-pentamethyl-17,19-dioxoandrosta-11,15-diene-14-carboxylate, methyl 3beta-acetoxy-15-hydroxy-4,4,8alpha,12,16-pentamethyl-17,19-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate
Definition: A 19-oxo steroid that is that is andrastin B in which the hydroxy group at position 19 has been oxidised to give the corresponding aldehyde. A farnesyltransferase inhibitor produced by Penicillium roqueforti, a filamentous fungus involved in the ripening of several kinds of blue cheeses.
Ontology: ChEBI [CHEBI:142842]  ( EBI )

Relationships
is a type of: 5beta steroid 15-hydroxy steroid 17-oxo steroid 19-oxo steroid acetate ester enol meroterpenoid methyl ester steroid aldehyde
has_functional_parent: andrastin B
has_role: EC 2.5.1.58 (protein farnesyltransferase) inhibitor Penicillium metabolite
inverse is_conjugate_base_of: andrastin A(1-)
is_conjugate_acid_of: andrastin A(1-)