Term Name: | spiroiminodihydantoin |
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Synonyms: | 7-amino-1,3,6,8-tetraazaspiro[4.4]non-6-ene-2,4,9-trione |
Definition: | An azaspiro compound that is 1,3,6,8-tetraazaspiro[4.4]non-6-ene which is substituted by oxo groups at positions 2, 4, and 9. Both enantiomers are highly mutagenic products resulting from the oxidation of guanine and 8-oxo-7,8-dihydroguanine in DNA by reactive oxygen species. |
Ontology: | ChEBI [CHEBI:142623] ( EBI ) |