Term Name: | CHIC-35 |
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Synonyms: | (6S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide, Compound (S)-35, SIRT1 Inhibitor IV, (S)-35 |
Definition: | An organic heterotricyclic compound resulting from the formal fusion of the 2-3 bond of 5-chloroindole with the 2-3 bond of cycloheptanecarboxamide (the S enantiomer). It is a potent, cell-permeable, metabolically stable and selective inhibitor of the deacetylase SIRT1. |
Ontology: | ChEBI [CHEBI:142489] ( EBI ) |