Term Name: | 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
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Synonyms: | 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea, 3-(3-methyl-1,2-thiazol-5-yl)-1-(1-methylindol-5-yl)urea, N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, SB 204741, SB-204741, SB204741 |
Definition: | A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. |
Ontology: | ChEBI [CHEBI:140936] ( EBI ) |