Term Name: ANA-12
Synonyms: ANA12, N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide, TrkB antagonist
Definition: A secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of alpha-amino-epsilon-caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B).
Ontology: ChEBI [CHEBI:140465]  ( EBI )

Relationships
is a type of: 1-benzothiophenes caprolactams secondary carboxamide
has_functional_parent: 2-aminohexano-6-lactam anthranilic acid
has_role: antidepressant anxiolytic drug tropomyosin-related kinase B receptor antagonist