Term Name: | sepantronium bromide |
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Synonyms: | 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide, 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide, bromure de sepantronium, bromuro de sepantronio, sepantronii bromidum, sepantronium bromide, YM 155, YM-155 |
Definition: | An organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis. |
Ontology: | ChEBI [CHEBI:139608] ( EBI ) |