Term Name: | superparamagnetic iron oxide nanoparticle |
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Synonyms: | SPION, SPIONs, superparamagnetic iron oxide nanoparticles |
Definition: | An iron oxide nanoparticle consisting of a magnetic iron oxide core (usually magnetite, Fe3O4, or maghemite, gamma-Fe2O3). They may be coated with a biocompatible polymer or precipitated within the pores of a porous biocompatible polymer, which can be attached to cytotoxic drugs or antibodies. These can be targeted to the required area using external magnets; after the external magnetic field is removed, the particles no longer show magnetic interaction. |
Ontology: | ChEBI [CHEBI:139547] ( EBI ) |