Term Name: | precursor messenger RNA |
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Synonyms: | pre-mRNA, pre-mRNAs, precursor messenger RNAs, precursor mRNA, precursor mRNAs |
Definition: | An immature or incompletely processed mRNA molecule that needs to be processed before it becomes a fully functional mature mRNA. Pre-mRNA is synthesized from a DNA template in the cell nucleus by transcription and lacks structures that the mRNA requires. First all introns have to be removed from the transcribed RNA through a process known as splicing. Before the RNA is ready for export, a Poly(A)tail is added to the 3' end of the RNA and a 5' cap is added to the 5' end. |
Ontology: | ChEBI [CHEBI:139356] ( EBI ) |