Term Name: | rhosin |
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Synonyms: | (2R)-2-amino-3-(1H-indol-3-yl)-N'-[(E)-(quinoxalin-6-yl)methylidene]propanehydrazide, (quinoxalinylmethylidene-D-tryptophanyl)hydrazide, D-tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide, Rho Inhibitor |
Definition: | A D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs |
Ontology: | ChEBI [CHEBI:137693] ( EBI ) |