Term Name: | camostat |
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Synonyms: | 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate, 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate, camostat, camostat mesilate, camostatum, N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate |
Definition: | A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. |
Ontology: | ChEBI [CHEBI:135632] ( EBI ) |