Term Name: camostat
Synonyms: 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate, 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate, camostat, camostat mesilate, camostatum, N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
Definition: A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
Ontology: ChEBI [CHEBI:135632]  ( EBI )

Relationships
is a type of: benzoate ester carboxylic ester diester guanidines tertiary carboxamide
has_functional_parent: 4-guanidinobenzoic acid
has_role: anti-inflammatory agent anticoronaviral agent antifibrinolytic drug antihypertensive agent antineoplastic agent antiviral agent serine protease inhibitor
inverse is_conjugate_acid_of: camostat(1+)
is_conjugate_base_of: camostat(1+)