Term Name: | quininib |
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Synonyms: | 2-[(E)-2-(quinolin-2-yl)vinyl]phenol |
Definition: | A styrylquinoline that is trans-2-styrylquinoline in which the the phenyl group has been substituted at position 2 by a hydroxy group. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1. The major species at pH 7.3 |
Ontology: | ChEBI [CHEBI:133170] ( EBI ) |