Term Name: roxadustat
Synonyms: ASP1517, FG 4592, FG-4592, FG4592, HIF prolyl-hydroxylase inhibitor, N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, roxadustat, roxadustatum
Definition: An N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH).
Ontology: ChEBI [CHEBI:132774]  ( EBI )

Relationships
is a type of: aromatic ether isoquinolines N-acylglycine
has_role: EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor