Term Name: | entinostat |
---|---|
Synonyms: | BAY 86-5274, BAY86-5274, entinostat, entinostatum, MS 27-275, MS 275, MS-27-275, MS-275, N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide, N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester, pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate, SNDX 275, SNDX-275 |
Definition: | A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3). |
Ontology: | ChEBI [CHEBI:132082] ( EBI ) |