Term Name:	phosphonoformic acid
Synonyms:	carboxyphosphonic acid, dihydroxyphosphanecarboxylic acid oxide, Foscarmet, Foscarnet, PHOSPHONOFORMIC ACID, phosphonomethanoic acid
Definition:	Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Ontology:	ChEBI [CHEBI:127780] ( EBI )

Relationships

is a type of:	carboxylic acid one-carbon compound phosphonic acids
has_functional_parent:	formic acid phosphonic acid
has_role:	antiviral drug geroprotector HIV-1 reverse transcriptase inhibitor sodium-dependent Pi-transporter inhibitor
inverse has_functional_parent:	CMP-5'-phosphonoformic acid
inverse is_conjugate_base_of:	phosphonatoformate phosphonoformate(2-)
is_conjugate_acid_of:	phosphonatoformate phosphonoformate(2-)